Therapeutic Programs / Pipeline Overview
Synthesis layer over the canonical by-photo corpus. This page is a program map. Per-program narrative lives on the existing topic and entity pages; this page does not re-narrate program detail. Every substantive statement links back to a topic, entity, source note, or canonical by-photo Markdown. Where the source carries
Uncertain Spans(program codes, dates, exponents, dose tokens), the routing here defers to the owner page rather than hardening the value.
Overview
The corpus’s therapeutic content is distributed across four layers:
(1) the GBA-PD pilot range with Pipeline of GD & GBA-PD and per-
compound rows for Eliglustat,
Ambroxol,
Venglustat, and
PR001; (2) the four aSyn-targeting
program nav-roots (TAK-341 (MEDI1341), SNCA ASO (WAVE),
SNCA BTV (HDO) (PFR-4067-100), aSyn programs > aSyn Propagation Suppressor / aSyn Degrader) routed through
alpha-synuclein; (3) the
PARKN GT (Takeshi Hioki, PFR-4249-100) AAV9-Parkin gene-therapy
arc owned by parkn-gt
and parkin; and (4) the NLRP3 inhibitor (Marianthi) (PFR-4231-100) small-molecule arc owned by
nlrp3-inhibitor
and inflammation. Two further single-page
program references — TAK-071 cholinergic/muscarinic M1 PAM
(note;
md, with the ASO/PD
power-table fragment also visible on md)
and the Pipeline of LRRK2 > … > DNL201 (=GNE-7…) /
DNL151 (=BIIB12…) LRRK2 row — sit in
lrrk2 without a synthesis owner and
are tracked here as backlog. The Pipeline-of-PD competitor inventory
(Prasinezumab, Cinpanemab, Lu AF82422, ABBV-0805, Affitope PD01A /
PD03A, UB-312, NPT200-11, Anle138b, ABL301, UCB0599 / minzasolmin,
NITROME, AAV2-GAD / MeiraGTx, etc.) is treated as in-axis evidence
inside the relevant topic and is not promoted to a program row here.
Source / Page Ownership Rules
The map follows three placement rules so that no two pages claim ownership of the same program rows.
- Per-program nav-root anchors a single owner. When a program
has a dedicated
nav_pathfirst-entry (e.g.PARKN GT (Takeshi Hioki, PFR-4249-100),NLRP3 inhibitor (Marianthi) (PFR-4231-100),SNCA ASO (WAVE),SNCA BTV (HDO) (PFR-4067-100),TAK-341 (MEDI1341),aSyn programs,TAK-071,DNL151 (=BIIB12...),Pipeline of LRRK2), the owner is whichever existing topic/entity page narrates that program. Where two pages overlap (PARKN GT lives in both parkin and parkn-gt), the entity page is the canonical program view and the topic page delegates per-axis context. - Compound-page anchors GBA-PD pilot rows. Eliglustat / Ambroxol /
Venglustat / PR001 trial and biomarker rows live on the per-compound
entity pages; gba-therapeutics is the
strategy-comparison map across them and gba-pd is
the GBA-PD problem framing. The
biomarkers (GBA-PD pilot) page seeds biomarker
logic and is bounded by the same
20240722_181748→_181809source range. - Program matrix routes; it does not narrate. Each row in the
## Program Matrixtable below names exactly one owner page and one source-coverage anchor. Per-program detail (timeline, biomarker plan, decision tree, sample-size logic, competitor landscape) lives on the owner page, not here. Boundary contradictions (e.g. PARKN GT decision-matrix scope vs Lewy- pathology Parkin row; aSyn Tier 1 source delegation) are surfaced under Uncertainties / Boundary Notes but resolution is deferred to the owner page.
Program Matrix
The matrix below covers therapeutic programs that have either an
internal program code (PFR-…), an internal program lead, or a
dedicated nav_path first-entry in the corpus. Pipeline-of-PD
competitor row programs (Prasinezumab, Cinpanemab, Inzomelid /
NodThera / Selnoflast / Ventyx, etc.) are not promoted to rows
here; they live as in-axis evidence on
alpha-synuclein,
inflammation,
nlrp3-inhibitor,
or the corresponding sections/<slug> page.
| program | modality / target | owner page | source coverage anchor | KB status | notes |
|---|---|---|---|---|---|
| PR001 (LY3884961) | AAV / GBA gene therapy | pr001 | md, md, md, with PROPEL / PROVIDE / PROGRESS clinical-trial row continuation on md | entity (seed) | GBA-PD pilot range; see gba-therapeutics for cross-strategy comparison. |
| Ambroxol | Pharmacological chaperone / GBA activator | ambroxol | md, md | entity (seed) | Source flags null mutations as not useful targets. |
| Venglustat (GZ/SAR402671 / ibiglustat) | GCS inhibitor (SM) | venglustat | md, md | entity (seed) | MOVES-PD 52-week MDS-UPDRS II+III result reproduced on the entity page. |
| Eliglustat (Cerdelga) | GCS inhibitor (SM, marketed for GD1) | eliglustat | md, md | entity (seed) | PD relevance marked uncertain in source summary. |
| PARKN GT (PFR-4249-100) | AAV9 / Parkin (PRKN) gene therapy | parkn-gt | 19 sources: see entity Source Table; topic context in parkin | entity (seed) | Decision matrix excludes aSyn-related biomarkers — see boundary note below. |
| NLRP3 Inhibitor (Marianthi) (PFR-4231-100) | NLRP3 small molecule | nlrp3-inhibitor | 11 sources: see entity Source Table; topic context in inflammation | entity (seed) | Series 5c (TR06798980 / TR06802042 / TR06851074) is the lead chemistry per source. |
| TAK-341 / MEDI1341 | aSyn antibody (passive immunotherapy) | tak-341 | 5 sources: see entity Source Table; topic context in alpha-synuclein § Antibody and Immunotherapy Programs | entity (active) | md PK/PD model and md Clinical studies anchor the program; cross-pipeline rows on md, md, md. By-nav: tak-341-medi1341. |
| SNCA ASO (WAVE) | SNCA mRNA RNase-H ASO | snca-aso-wave | 1 source: see entity Source Table; topic context in alpha-synuclein § Antibody and Immunotherapy Programs / SNCA-Knockdown Programs | entity (active) | md Clinical plan of SNCA ASO anchors the program. By-nav: snca-aso-wave. |
| SNCA BTV (HDO) (PFR-4067-100) | BTV-conjugated heteroduplex oligonucleotide (HDO) targeting SNCA | snca-btv-hdo | 1 source: see entity Source Table; topic context in alpha-synuclein § Antibody and Immunotherapy Programs / SNCA-Knockdown Programs | entity (active) | md Executive summary (Ryouta Maeda) anchors the program. By-nav: snca-btv-hdo-pfr-4067-100. |
| aSyn programs umbrella (aSyn Propagation Suppressor / aSyn Degrader) | Small-molecule phenotypic-screen umbrella | asyn-propagation-suppressor | 1 source: see entity Source Table; topic context in alpha-synuclein § Antibody and Immunotherapy Programs / SNCA-Knockdown Programs umbrella | entity (active) | md aSyn programs > aSyn Propagation Suppressor page anchors the SM Propagation Suppressor / aSyn Degrader axis. By-nav: asyn-programs. |
| TAK-071 | Cholinergic / muscarinic M1 PAM | gba-pd-asyn (single source) | md; related power-table fragment on md | section-only | No topic synthesis; backlog candidate for an entity page. By-nav: tak-071. |
| DNL151 (=BIIB12…) | LRRK2 kinase inhibitor (Denali / Biogen) | lrrk2 (single source) | md | section-only | No topic synthesis; backlog candidate. By-nav: dnl151-biib12. |
| DNL201 (=GNE-7…) | LRRK2 kinase inhibitor (Denali / Genentech) | lrrk2 (single source, sub-path) | md under Pipeline of LRRK2 > Summary (Schneider…) > DNL201 (=GNE-7…) > Clinical trials | section-only | No topic synthesis; backlog candidate. By-nav: pipeline-of-lrrk2. |
| GAPFREE3 / Preclinical support (MC1 PET radioligand bench) | [3H]BCPP-EF saturation-binding bench on PARK2 / sPD fibroblasts | parkin § Preclinical Support And MC1 PET Radioligand Work | md, md, md, md, with iPSC adjacency on md | topic-only | No standalone program / entity page; the radioligand work supports the PARKN GT MC1 PET biomarker plan. |
Across the 14 program rows (4 GBA-PD pilot rows: PR001, Ambroxol,
Venglustat, Eliglustat; 2 internal-program-code rows: PARKN GT,
NLRP3 Inhibitor; 4 aSyn-cluster rows: TAK-341, SNCA ASO, SNCA BTV,
aSyn programs umbrella; 1 single-page cholinergic row: TAK-071;
2 LRRK2 rows: DNL151, DNL201; 1 radioligand-bench row: GAPFREE3 /
Preclinical support), source coverage anchors the matrix to
existing topic/entity pages or to source notes for single-page
programs. The KB status column distinguishes entity (seed) /
entity (active) rows (have a dedicated entity page; the aSyn
programs umbrella (aSyn Propagation Suppressor / aSyn Degrader),
SNCA ASO (WAVE), SNCA BTV (HDO) (PFR-4067-100), and TAK-341 /
MEDI1341 are the most recent active promotions, leaving all four
aSyn-cluster rows on entity pages) from topic-only (Tier 1) rows
(narrated inside an existing topic-level synthesis) and
section-only rows (only listed by section / by-nav, no synthesis).
The matrix excludes pure-competitor / external-pipeline rows; see
the topic pages for the in-axis competitor inventory.
Existing Entity Pages
These entity pages are the canonical program views in the KB. Source counts and provenance totals come from each entity’s own Source Table; this page does not duplicate them.
| entity | type | program code | program lead | owner section | owner topic |
|---|---|---|---|---|---|
| pr001 | program | LY3884961 (Prevail) | — | gba-pd-asyn | gba-therapeutics, gba-pd |
| parkn-gt | program | PFR-4249-100 | Takeshi Hioki | parkin | parkin |
| nlrp3-inhibitor | program | PFR-4231-100 | Marianthi | inflammation | inflammation |
| tak-341 | program | — (Takeda / AstraZeneca / MedImmune) | — | gba-pd-asyn | alpha-synuclein |
| snca-btv-hdo | program | PFR-4067-100 | Ryouta Maeda | gba-pd-asyn | alpha-synuclein |
| snca-aso-wave | program | — (Takeda / Wave Life Sciences) | — | gba-pd-asyn | alpha-synuclein |
| asyn-propagation-suppressor | program | — | — | gba-pd-asyn | alpha-synuclein |
| ambroxol | compound | — (ABX) | — | gba-pd-asyn | gba-therapeutics |
| venglustat | compound | GZ/SAR402671 | — | gba-pd-asyn | gba-therapeutics |
| eliglustat | compound | Cerdelga | — | gba-pd-asyn | gba-therapeutics |
Programs Covered By Topic Pages Only
These programs are narrated inside an existing topic synthesis but do not have a standalone entity page. The owner topic carries the per-axis narrative; the by-nav indexes carry per-stem coverage.
| program | owner topic axis | owner section | by-nav index | source-note | canonical |
|---|---|---|---|---|---|
Pipeline of PD aSyn - Antibody / Small molecules / Vaccine competitor inventory | alpha-synuclein § Antibody and Immunotherapy Programs (Pipeline of PD rows) | gba-pd-asyn | pipeline-of-pd | note, note, note | md, md, md |
Pipeline of PD GT row (AAV2-GAD / MeiraGTx, UB-312, PD01A long-term, MEDI1341 SAD) | clinical-pd | clinical-pd | pipeline-of-pd | note | md |
GAPFREE3 / Preclinical support ([3H]BCPP-EF MC1 PET radioligand bench) | parkin § Preclinical Support And MC1 PET Radioligand Work | parkin | gapfree3, gapfree3-ipsc-yuya-kunisada, preclinical-support | note, note, note, note, note | md, md, md, md, md |
Entity Backlog Candidates
These programs are visible in existing KB pages but do not yet have a
dedicated entities/programs/<slug>.md or entities/compounds/<slug>.md
page. They are listed here as backlog only; this pass does not
create any new entity pages. Promotion is gated by enough source
material (or owner page narrative) to support a per-program
Evidence Package and Source Table.
| backlog candidate | rationale to promote | owner / source pointer | suggested entity slug |
|---|---|---|---|
| TAK-071 | Single Tier 1 source with Mechanism, TAK-071 PD Falls and cognition Timelines – Base Plan, Timeline of TAK-071, TM of TAK-071 headings; cross-reference power-table fragment on the SNCA ASO page. | gba-pd-asyn; note | entities/programs/tak-071 |
| isofagomine | Mentioned in the GBA-PD pilot summary area before eliglustat (gba-therapeutics Strategy Map row) and on adjacent GBA-PD pages. Coverage is light — promote only if cross-page evidence justifies an entity page. | gba-therapeutics; md, md, md, md, md, md | entities/compounds/isofagomine |
| GAPFREE3 (program) | Multiple nav_path first-entries (GAPFREE3, GAPFREE3 (iPSC, Yuya Kunisada), GAPFREE3 > Preclinical support, GAPFREE3 > Preclinical support > ARG); the radioligand bench supports PARKN GT MC1 PET. Owner topic narrates but does not isolate the program. | parkin; note, note, note | entities/programs/gapfree3 |
| DNL151 (=BIIB12…) / DNL201 (=GNE-7…) | LRRK2 kinase inhibitor program (Denali / Biogen / Genentech). Two single-source rows with preclinical and clinical-trial headings. | lrrk2; note, note | entities/programs/dnl151 (or umbrella denali-lrrk2) |
| AAV2-GAD / MeiraGTx | Listed under the Pipeline of PD > GT row on 20240722_184333 alongside UB-312 / Vaxxinity, PD01A long-term notes, and active-vs-passive-immunisation pros/cons. Currently no owner topic. | clinical-pd; note | entities/programs/aav2-gad |
Pipeline-of-PD competitor rows that surface inside the alpha-synuclein § Antibody and Immunotherapy Programs axis (Prasinezumab, Cinpanemab, Lu AF82422, ABBV-0805, Affitope PD01A / PD03A / ACI-7104 / VacSYn, UB-312 / Vaxxinity, NPT200-11 / Neuropore, Anle138b / MODAG / TEVA, ABL301 / ABL Bio / Sanofi, UCB0599 / minzasolmin, BIIB101 / ION464 / Ionis, NITROME) are external comparators, not internal programs. They are not entity-backlog candidates in this pass; the canonical home for their per-program detail is the same topic axis. The same applies to the NLRP3 inhibitor competitor inventory carried by nlrp3-inhibitor (Inzomelid / Inflazome / Roche, Selnoflast / RO7486967 / RG-6418, NodThera NT-0796 / NT-0249 / NT-0527, Ventyx VTX-2735 / VTX-3232, Ventus VENT-02, Novartis DFV890 / IFM 2427, Dapansutrile / Olatec, Neumora, Halia, Genali, MCC950).
Cross-topic Dependencies
Programs sit across multiple topic clusters. The dependencies below are routing pointers, not double-narration.
- GBA-PD ↔ aSyn. PR001 / Ambroxol / Venglustat / Eliglustat per-compound CSF total / phospho / insoluble / proteinase-K-resistant α-syn readouts are recorded on the per-compound entity pages and on the GBA-PD pilot pages. The whole-page α-syn synthesis is the Tier 1-only alpha-synuclein; per the alpha-synuclein source boundary map, the GBA-PD pilot range is delegated to gba-pd / gba-therapeutics and the per-compound entity pages.
- PARKN GT ↔ aSyn / Mitochondria / PET-Imaging. PARKN GT
(parkn-gt)
carries an aSyn PFF preclinical-model row in its in-vivo evidence
table while explicitly excluding aSyn-related biomarkers from its
clinical biomarker plan. MC1 PET /
[18F]BCPP-EFis the program’s imaging biomarker (delegated to mitochondria for tracer mechanism context and to pet-imaging for tracer-development framework). Parkin PET TE biomarker work is delegated to the parkin § Preclinical Support And MC1 PET Radioligand Work axis. - NLRP3 Inhibitor (Marianthi) ↔ Inflammation / PET-Imaging /
Biomarkers-Outcomes. The program’s Microglial Imaging axis
([18F]DPA714 / [18F]FEPPA, TSPO
rs6971Ala147Thr) bridges inflammation § Imaging Neuroinflammation and pet-imaging § Microglial Imaging — TSPO. The ADAssays of pyroptosiscytokine / chemokine omics axis bridges to biomarkers-outcomes. The Havrda / Katy KOL strands are owned by inflammation § Competitor / In Vivo Strategy / KOL (Havrda, Katy). - TAK-341 / SNCA ASO / SNCA BTV ↔ aSyn / PET-Imaging. All three
aSyn-targeting programs carry a PET workstream — TAK-341 PK/PD model
with
MEDI1341 brain penetration 0.1 %, SNCA ASOPET SNCA ASObiodistribution plan, SNCA BTVHDO PET Development Workflow(Steps 1–4 with Paul McQuade questions). PET tracer-development context lives on pet-imaging; the program-specific PET plans live on alpha-synuclein § Antibody and Immunotherapy Programs. - Pipeline-of-PD comparators ↔ aSyn / inflammation / LRRK2.
Cross-program comparator rows on
20240722_184324/20240722_184327/20240722_184330/20240722_184333(Pipeline-of-PD aSyn-Antibody, aSyn-Small molecules, aSyn-Vaccine, GT) link cleanly into alpha-synuclein; the LRRK2 row is delegated to lrrk2. - GBA-PD ↔ Biomarkers-Outcomes. Biomarker-development framework,
scales (UPDRS / MoCA / RBD / SCOPA-AUT), NFL, and sample-size logic
for GBA-PD trials live on
biomarkers-outcomes;
the seed biomarkers (GBA-PD pilot) page is
bounded to the same
20240722_181748→_181809source range as the GBA-PD pilot.
Compact Provenance Table
This table lists one source-coverage anchor per program row (the source most central to the program’s narrative on its owner page). It is not a replacement for the per-program Source Tables on the entity / topic pages. Cross-program coverage continues there.
| program | anchor stem | nav path / heading | source note | canonical |
|---|---|---|---|---|
| PR001 (LY3884961) | 20240722_181809 | Pipeline of GD & GBA-PD > Prevail PR001 | note | md |
| Ambroxol | 20240722_181756 | Pipeline of GD & GBA-PD > Venglustat (Ibiglustat) | note | md |
| Venglustat | 20240722_181800 | Pipeline of GD & GBA-PD > Prevail PR001 | note | md |
| Eliglustat | 20240722_181748 | Pipeline of GD & GBA-PD > Summary | note | md |
| PARKN GT (PFR-4249-100) | 20240722_182021 | Parkin > PARKN GT (Takeshi Hioki, PFR-4249-100) | note | md |
| NLRP3 Inhibitor (Marianthi) (PFR-4231-100) | 20240722_183153 | Pipeline of Inflammation > Pipeline CAPS > Animal model > TM > NLRP3 inhibitor (Marianthi) (PFR-4231-100) | note | md |
| TAK-341 / MEDI1341 | 20240722_181818 | Pipeline of GD & GBA-PD > TAK-341 (MEDI1341) > PK/PD model | note | md |
| SNCA ASO (WAVE) | 20240722_181835 | SNCA ASO (WAVE) > Clinical plan of SNCA ASO | note | md |
| SNCA BTV (HDO) (PFR-4067-100) | 20240722_181831 | SNCA BTV (HDO) (PFR-4067-100) > Executive summary (Ryouta Maeda) | note | md |
| aSyn programs umbrella | 20240722_181827 | aSyn programs > aSyn Propagation Suppressor | note | md |
| TAK-071 | 20240722_181839 | TAK-071 > Mechanism | note | md |
| DNL151 (=BIIB12…) | 20240722_183410 | DNL151 (=BIIB12…) > Clinical trials > Preclinical | note | md |
| DNL201 (=GNE-7…) | 20240722_183407 | Pipeline of LRRK2 > Summary (Schneider…) > DNL201 (=GNE-7…) > Clinical trials | note | md |
| GAPFREE3 / Preclinical support | 20240722_184138 | GAPFREE3 > Preclinical support | note | md |
Uncertainties / Boundary Notes
These are routing-level uncertainties. Per-program Uncertain Spans
are owned by the source notes and the owner pages; this list captures
only the cross-program / map-level boundary issues worth flagging
before any downstream extraction.
- PARKN GT decision-matrix scope contradiction. The decision
matrix on md records
that aSyn-related biomarkers are not planned for PARKN GT because
aSyn pathology is rarely observed in the target population, while
the Lewy-pathology Kalia and Kalia table on
md records Parkin as
+for protein-in-LB and+/-for LB-associated-with-disease. The same contradiction is recorded on parkin and on alpha-synuclein § Parkin / PARKN GT ↔ aSyn Link; the alpha- synuclein source boundary map also flags it. - NLRP3 Inhibitor program-source vs nav-root scoping. Of the 11
sources on
nlrp3-inhibitor,
only 2 carry the program nav root as their first
nav_pathentry (per the entity’sSource Scope And Boundary Notes). The Havrda KOL / Katy in-vivo pages (20240722_183225,_183228,_183234,_183238,_183241) are tightly coupled to the program in content but do not reference the program nav root, so they are catalogued at the topic level under inflammation § Competitor / In Vivo Strategy / KOL (Havrda, Katy) instead. Re-check before promoting any to entity-page rows. - PARKN GT trailing-comma / GBA-PD-section overlap.
20240722_182103is filed undersections/gba-pd-asynbecause the discovery layer assigned it to the GBA-PD cluster from its PE I Imaging GBA / PRC1 PE narrative content, but its firstnav_pathentry isPARKN GT (Takeshi Hioki, PFR-4249-100) > RD DDU's PET Imaging GBA > PK/PD Strategy, so the entity page includes it.20240722_182113carries the trailing-commaParkin,first nav root rather than the long PARKN GT heading, so it is not in the per-nav-root index but is included in the entity page’s Source Table. Map consumers should follow the entity-page Source Table for canonical PARKN GT scope. - aSyn Tier 2 / Tier 3 delegation. Per the alpha-synuclein source boundary map, 145 Tier 2 and 54 Tier 3 candidate aSyn sources are delegated to sibling topic syntheses or section pages and are not re-narrated on alpha-synuclein. This page does not promote any of them to a program row; the Pipeline-of-PD competitor inventory is the only multi-program block surfaced via the topic page, not via this map.
- Single-source backlog risk. TAK-071, GAPFREE3, and DNL151 /
DNL201 each have 1–2 source pages of evidence. Promoting any of
them to an entity page should follow the
parkn-gt /
nlrp3-inhibitor /
tak-341 /
snca-btv-hdo /
snca-aso-wave /
asyn-propagation-suppressor /
pr001 precedent
(Evidence Package + Source Table + Uncertainties Carried From
Source) and should preserve
Uncertain Spansrather than paraphrase them. The newly promoted asyn-propagation-suppressor (1 source: the singleaSyn programs > aSyn Propagation Suppressorpage, sharing the upper portfolio-grid fragment with the sibling SNCA BTV / SNCA-ASO / TAK-341 program rows that are delegated out), snca-aso-wave (1 source: the single SNCA ASO (WAVE) Clinical plan of SNCA ASO page, sharing the canonical photo with TAK-071 content that is delegated out), and snca-btv-hdo (1 source: the single SNCA BTV (HDO) (PFR-4067-100) Executive summary page) are the closest precedents for a single-source aSyn-program entity, alongside tak-341 (5 sources: 2 TAK-341 nav-rooted primary pages + 3 Pipeline-of-PD cross-pipeline pages) for a small-source aSyn-program entity. - Pipeline-of-PD competitor scope. The competitor rows on
20240722_184324/20240722_184327/20240722_184330/20240722_184333(Prasinezumab dose / weight strata, PASADENA trial-design, ABBV-0805, Affitope PD01A / PD03A, UB-312, NPT200-11, Anle138b, ABL301, UCB0599 / minzasolmin, BIIB101 / ION464, AAV2-GAD / MeiraGTx) carry severalUncertain Spansfor token-list drug names and clipped result cells. Treat them as in-axis evidence, not as program rows. - Body-purity figure-embed boundary. Per
docs/decisions/2026-04-29-body-purity-and-figure-only-embeds.md, several program pages embed only figure-only crops; mixed text-and- figure crops are kept as evidence rather than embedded. This page re-uses owner-page provenance and does not re-embed figures.
Related Pages
- Owner topics: gba-pd, gba-therapeutics, parkin, inflammation, mitochondria, biomarkers-outcomes, pet-imaging, alpha-synuclein, biomarkers (GBA-PD pilot).
- Owner entities (program / compound): pr001, parkn-gt, nlrp3-inhibitor, tak-341, snca-btv-hdo, snca-aso-wave, asyn-propagation-suppressor, ambroxol, venglustat, eliglustat.
- Sections touched by the program map: gba-pd-asyn (198), parkin (46), inflammation (42), biomarkers-outcomes (27), mitochondria (19), pet-imaging (16), lrrk2 (4), clinical-pd (9), msa (9).
- Per-nav-root indexes for the program rows: parkn-gt-takeshi-hioki-pfr-4249-100, nlrp3-inhibitor-marianthi-p, tak-341-medi1341, snca-aso-wave, snca-btv-hdo-pfr-4067-100, asyn-programs, tak-071, dnl151-biib12, pipeline-of-lrrk2, pipeline-of-gd-and-gba-pd, pipeline-of-pd, pipeline-of-inflammation, pipeline-msa, gapfree3, gapfree3-ipsc-yuya-kunisada, preclinical-support, gt.
- Maps: source-catalog, nav-path-index, document-outline, alpha-synuclein-source-boundary.
- KB structure: KB Index, Build Note, Sidebar, Build Log.