Delta oscillation reflects the burst-pause firing pattern of the hyperpolarized thalamic cortex and corticothalamic neurons in synchronization (Steriade et al., 1993). Delta activity can be measured by delta power by Fourier analysis.
Higher sleep quality,
a biomarker of homeostatic sleep drive, as evidence shows that delta power is enhanced after prolonged wakefulness, but declines as sleep deepens.
delta power is often accompanied by sleep duration and intensity (Davis et al., 2011
a deceased delta change accompanies higher sleep quality during REM period
↑ {Memon, 2023 #2386}
Theta power (4–8 Hz)
={Memon, 2023 #2386}
B power (12–30 Hz)
={Memon, 2023 #2386}
Effect size (continued)
Mean PD
Mean HC
% difference
SD PD
SD HC
%CV PD
%CV HC
CV (SD/Mean)
Effect size (d, vs CTL)
α
β
tail
N needed per group to detect the group difference (vs CTL)
Sample size per group in a clinical trial to detect 50% correction
Sample size per group in a clinical trial to detect 75% correction
These SD and CV values are all group parameters, not for difference!
ES
N per group
150
100
150%
75
50
50%
50%
0.5
0.78
0.1
0.7
One
12
1.5
0.1
0.7
One
4
1.5
0.1
0.8
One
5
0.75
17
1.5
0.05
0.8
One
7
0.75
23
1.18
0.1
0.7
One
6
0.97
0.1
0.7
One
8
0.97
0.1
0.8
One
11
0.97
0.05
0.8
One
14
31
1.1
0.1
0.8
One
0.97
130%
0.43
0.91
0.05 0.8 one
21
0.4
78
150
100
0.8
0.1 0.7 One
11
0.4
42
150%
0.5
0.78
0.1 0.7 One
12
44
0.70
54 (?)
0.67
0.1 0.7 One
15
59
0.647
17
130%
0.41 (
0.63
17
130%
0.43
0.6
0.05 0.8 one
36
0.3
139
130%
0.5
0.6
0.1 0.7 One
19
0.3
73
0.5
20
78
0.5
27
0.5
0.05 0.8 two
64
0.44
0.1 0.7 One
35
136
0.37
0.1 0.7 One
49
192
0.335
0.1 0.7 One
59
0.30
0.1 0.7 One
73
0.27
90
359
0.185
0.1 0.7 One
192
post-hoc
% difference
CV
(observed 겠지) Effect size
α
tail
N of group 1
N of group 2
Power (1-β)
p-value
1.18
0.78
0.70
0.67
0.1
One
0.647
130%
0.43
0.60
19
19
71%
130%
0.43
0.60
33
10
64%
130%
0.43
0.60
28
7
55%
0.065
150%
0.43
0.91
19
19
93%
150%
0.43
0.91
33
10
89%
150%
0.43
0.91
28
7
80%
130%
0.5
0.52
19
19
62%
130%
0.5
0.52
33
10
55%
130%
0.5
0.52
28
7
47%
150%
0.5
0.78
19
19
T test (independent group)
87%
150%
0.5
0.78
33
10
81%
150%
0.5
0.78
28
7
71%
0.02
150
0.5
0.78
0.05
Two
24
24
76%
number of samples
literatures: d= 1.5-3,
servative approach: 미래, but we target d=0.58 , we need 20, ☒ 78 patients per group in a clinical
NLRP3 (or ASC) vs TH
plan
CTL+NU+PD?
β
α
tail
N needed (control + PD)
0.5
0.1
one
13
0.6
9
0.7
7
0.6
0.05
one
15
0.5
0.05
one
23
correlation / Exact test
α
β
tail
Exact test
N needed to achieve statistical significance
0.1
0.7
One
13
0.1
0.8
one
17
0.05
0.8
one
0.1
0.7
one
0.1
0.7
one
23
0.1
0.8
one
18
0.05
0.8
one
0.05
0.7
one
23
0.05
0.7
two
29
0.05
0.8
two
12
0.1
0.7
two
15
0.1
0.8
Two
0.05
0.8
Two
Uncertain Spans
location
transcription
uncertainty
Effect size / 0.41 (
a row shows effect size value 0.41 ( with an unclosed parenthesis preceding the embedded NLRP3 chart.
the trailing parenthesis is a typo / hanging artifact in the source.
Effect size / 54 (?) cell
the N per group cell at the row with effect size 0.70 reads 54 (?) with a literal (?) in the source.
author’s own uncertainty marker.
Effect size / row 22 / 8
the row associated with effect size 0.5 and N=20 also has another adjacent value 8 in some neighboring cell; alignment is approximate.
dense matrix, multiple 0.5 rows.
Effect size / 21 and 27 and 64 and 15 and 17 and 36 rows
repeated effect size value 0.5 with multiple sample-size variations across α/β/tail combinations; rows may have tilted column boundaries.
matrix density.
notes / servative approach: 미래
left edge of the line is clipped; visible text begins at servative approach, likely truncating conservative; following Korean glyph reads 미래 (future) but is a partial fragment.